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South American gaucho with horse in traditional dress

south america

South America offers vast landscapes, diverse cultures, and real opportunities to live well for less. From the Andes to the Amazon, cities to quiet pueblos, this region is drawing expats, remote workers, and early retirees seeking freedom, affordability, and adventure. Discover where in South America you can build a life that actually works.

Panoramic night view of Medellín, Colombia, from a luxury penthouse in the Poblado district, showcasing one of the best cities in South America.

5 Best Cities to Live in South America

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9 min read

Looking for the best places to live in South America? Whether you're an expat, retiree, or remote worker, this guide covers five top cities offering safety, affordability, and great quality of life.

Want to know if you qualify for residency in a South american country?

If you’re considering making South America your next home, our FREE Latin America Residency Map
shows you which countries you might already qualify for — including digital nomad and pension programs.

You’ll also be the first to know when we publish new guides about living in South America.