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5 Best Cities to Live in South America

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We’re Philip and Lin, and we’re here to help you explore the exciting possibilities of living in Latin America. Whether you’re thinking about relocating, starting a business, or simply seeking new opportunities, we’ve got plenty of tips and resources to guide you. While we’re not experts in every corner of the region, our passion for living life on our own terms has inspired us to share our journey and insights with you!


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sOUTH AMERICA

9 min read

City lights, mountain views, and rooftop living—South America’s top cities offer more than charm. For expats, retirees, and remote workers, these five standout spots combine safety, affordability, and a surprisingly high quality of life.

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Understanding the Dynamics: Why Live In South America?

South America is a continent of incredible diversity, offering everything from vibrant urban centers to peaceful coastal towns and breathtaking mountain landscapes.

Whether you’re drawn to the rhythm of bustling cities or the serenity of nature, South America has something for everyone. In this blog post, we’ll take a closer look at five of the best cities to live in South America—each offering a unique blend of culture, affordability, quality of life, and opportunity.

From the tropical charm of Rio de Janeiro to the innovative energy of Medellín, these cities are not just places to visit, but to thrive. Let’s explore why South America is becoming an increasingly popular destination for expats and digital nomads alike.

A bar chart showing the cost of living of various cities including South America.

1. Buenos Aires, Argentina: Why Expats Choose to Live in South America

Aerial view of Avenida 9 de Julio in Buenos Aires, Argentina — a vibrant urban hub for those looking to live in South America

An aerial shot of Avenida 9 de Julio, one of the most iconic streets in Buenos Aires, Argentina, bustling with traffic and framed by historic architecture.

Cost of living chart for Buenos Aires, Argentina, comparing expenses for a single person and a family.


Buenos Aires is a dynamic city that blends rich history with a modern, cosmopolitan edge. Known for its striking architecture, passionate tango culture, and mouthwatering cuisine, it stands out as one of the top cities to live in South America.

What makes Buenos Aires truly special is its electric energy — the kind that draws people from all walks of life to stay, settle, and thrive. From the leafy streets of Palermo to the timeworn charm of San Telmo, it’s a place that offers both variety and soul.

Whether you’re into arts, nightlife, or connecting with warm, welcoming locals, Buenos Aires continues to capture the hearts of those looking to live in South America with meaning and style.

Affordability is a major perk. Compared to other global capitals, Buenos Aires lets you enjoy more for less. Grab a street-side choripán, indulge in empanadas or medialunas, and browse lively neighborhood markets — all without breaking your budget. The city’s food scene is deeply local, proudly simple, and endlessly satisfying.

Housing is equally accessible. Whether you prefer the bohemian vibe of Palermo, the historical roots of San Telmo, or Recoleta’s elegant calm, you’ll find rentals that match your style and budget. Buenos Aires gives you real choices — a key reason it’s so often recommended for people considering where to live in South America.

Transportation is cheap and reliable, with extensive bus lines and the Subte (subway) connecting the city’s many neighborhoods. Even taxis are affordable, making it easy to explore at your own pace.

Entertainment, culture, and green spaces are everywhere. From open-air tango shows to art exhibits and weekend markets, the city invites you to enjoy it without spending much. Even a shared mate in a public plaza becomes part of the daily rhythm — a simple, authentic way to engage with life here

South America is full of underrated gems for expats and remote workers—this guide covers 5 of the best cities to live in. Want to explore more? Check out our full list of countries and places to live in South America.

2. Rio de Janeiro, Brazil: Life in One of the Best Places to Live in South America

Sunset over the city of Rio de Janeiro, Brazil, with a view of the skyline, Sugarloaf Mountain, and Copacabana Beach illuminated by warm golden light.

A sunset paints the sky over Rio de Janeiro, Brazil, casting a golden glow over the city’s iconic skyline. Rio de Janeiro’s natural beauty and vibrant culture make it one of the top cities to live in South America.

Cost of living chart for Rio de Janeiro, Brazil, comparing expenses for a single person and a family.

Rio de Janeiro, a city full of life and beauty, is nestled between stunning beaches and lush green mountains. It’s one of the most iconic places to live in South America, offering a blend of natural wonders, cultural richness, and nonstop energy that captures the hearts of expats, nomads, and locals alike.

Famous landmarks like Christ the Redeemer and Sugarloaf Mountain give Rio a cinematic skyline — but it’s the rhythm of everyday life that makes it unforgettable. The city’s legendary Carnival, lively nightlife, and warm, welcoming locals create a dynamic environment for those looking to live in South America with excitement and flair.

Whether it’s the jaw-dropping scenery, the cultural depth, or the infectious spirit of the city, Rio attracts people from around the world seeking a freer, more vibrant way of life.

The food scene is as colorful as the city itself. From savory feijoada to fresh açaí, Rio caters to every palate and budget. Street vendors and beachside kiosks serve up tasty, affordable bites that reflect Brazil’s rich culinary heritage — perfect for those seeking a flavorful, budget-conscious way to live in South America.

Each neighborhood in Rio tells its own story. From the artistic streets of Santa Teresa to the beach bliss of Copacabana and the upscale vibe of Ipanema, there are options for every budget and lifestyle. Whether you’re renting a modest apartment or a scenic coastal flat, you’ll find a rhythm that fits.

Getting around is easy and affordable. Rio’s public transport — including buses, metro lines, and iconic yellow taxis — makes commuting accessible, while the city’s bike-share system lets you explore at your own pace.

Entertainment is everywhere. From samba in Lapa to street parties and beach hangouts, the city offers a full social calendar without the high price tag. And of course, the beach isn’t just a weekend spot — it’s the soul of the city.

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3. Medellín, Colombia: What It’s Like to Live in South America

Night view of Medellín, Colombia, with the city's skyline and hills lit up, showcasing a vibrant urban landscape.

The dynamic skyline and surrounding hills showcase why Medellín is considered one of the top cities to live in South America.

Cost of living chart for Medellín, Colombia, comparing expenses for a single person and a family.

Medellín, in the heart of Colombia, is one of the most compelling places to live in South America. Surrounded by lush green mountains and known as the “City of Eternal Spring,” it offers year-round mild weather, stunning views, and an inviting pace of life that’s hard to match.

But Medellín is more than just a pretty backdrop. Its people are warm and welcoming, and the city itself has undergone a powerful transformation. Once plagued by violence, Medellín is now a global model for urban renewal — making it a rising favorite for those looking to live in South America without sacrificing infrastructure or innovation.

Efficient public transport, including metro lines and cable cars, connects neighborhoods across the Aburrá Valley.

The food scene? Local staples like bandeja paisa and fresh arepas keep things flavorful and budget-friendly. Markets overflow with fresh produce, making healthy living affordable.

Medellín offers a range of neighborhoods to match different lifestyles. From the creative energy of El Poblado to the traditional charm of Laureles or Envigado’s emerging expat scene, there’s something for everyone.

Free public spaces, cultural festivals, and a genuine sense of community make this city a standout choice for those ready to live in South America on their own terms — with connection, culture, and quality of life at the center.

4. Quito, Ecuador: A Great Choice to Live in South America

Clouds floating over the hills surrounding Quito, Ecuador, with the city visible below, showcasing the stunning landscape.

A serene view of clouds drifting over the hills surrounding Quito, Ecuador, with the city nestled in the valley below. The breathtaking natural beauty and vibrant culture make Quito one of the top cities to live in South America.

Cost of living chart for Quito, Ecuador, comparing monthly expenses for a single person and a family, covering categories like housing, food, and transportation.

Quito, the capital of Ecuador, is a lively urban hub perched high in the Andes Mountains — and one of the most intriguing places to live in South America.

With its colonial architecture, dynamic neighborhoods, and awe-inspiring landscapes, Quito blends history and modern life in a way few cities can. As a UNESCO World Heritage Site, Quito showcases its cultural depth through beautifully preserved buildings and a seamless mix of indigenous and Spanish influences.

But it’s not just for history buffs — those who choose to live in South America will find Quito’s creative energy, booming culinary scene, and laid-back rhythm equally compelling.

Neighborhoods range from the cobblestone charm of the Old Town to the artistic vibe of La Floresta and the modern bustle of La Carolina. There’s something here for every lifestyle and budget — a major draw for those seeking to live in South America affordably without compromising on culture or comfort.

Quito’s commitment to public life shines in its museums, parks, and free community events. Whether you’re strolling through La Carolina Park or soaking up Andean history in the city’s plazas, the capital offers a daily rhythm that feels both rich and accessible.

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5. Huanchaco, Peru: Coastal Living When You Live in South America

A deserted upscale street in a town in Peru, featuring elegant buildings, cobblestone streets, and a peaceful, serene atmosphere.

A quiet, deserted upscale street in a charming town in Peru, showcasing the peaceful atmosphere and elegant architecture. This image reflects the serene lifestyle that makes certain towns in Peru some of the top cities to live in South America.

Cost of living chart for Huanchaco, Peru, showing monthly expenses for a single person and a family, including housing, food, and transportation.

Huanchaco, a laid-back coastal town in northern Peru, is a hidden gem for those looking to live in South America with ocean views and a slower pace.

Known for its surf culture, golden beaches, and iconic reed boats called caballitos de totora, this town offers a relaxed, beach-focused lifestyle that’s hard to beat.

For history lovers who want to live in South America without giving up cultural depth, Huanchaco delivers. Its pre-Inca roots, nearby archaeological sites, and rich traditions provide endless opportunities to explore Peru’s heritage.

From fresh ceviche at beach shacks to affordable produce at local markets, eating well here doesn’t cost a fortune. And with walkable streets, local buses, and easy access to Trujillo, getting around is simple and budget-friendly.

And let’s not forget the warmth of the local community, where a friendly “hola” (hello) is never far away. The expat community in Huanchaco is welcoming, creating a sense of belonging for those seeking a tranquil escape by the sea.

Whether you’re dreaming of a beachfront cabana or a modest apartment, Huanchaco has housing options to match your lifestyle. It’s the kind of place where people come to live in South America not just for the view — but for the peace of mind.

If you’re seeing Latin America through a different lens now, explore the 10 major advantages of living here—you might be surprised what’s possible.

Wrapping Up: How to Decide Where to Live in South America

South America is an incredibly diverse region to explore and live in South America. Countless cities offer a high standard of living at much lower costs than many other countries.

From the pulsating rhythms of Rio de Janeiro to the historic elegance of Buenos Aires, the eternal spring of Medellín, the vibrant culture of Quito, and the laid-back coastal haven of Huanchaco, these cities stand out not only for their captivating atmospheres but also for their remarkable affordability.

Deciding where to live in South America is a very personal choice; however, understanding the cost of living in each city should be a key factor.

The good news is that leading a comfortable life with access to medical care, great food, and entertainment doesn’t have to cost the world anymore!

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